Intel Core i7-3960X <- most important bit get a bloody good motherboard as well
I personally would never spend the money on a Quadro total waste IMO spend any savings on decent ram and the above processor. Any GPU with a gig plus of ram on it will do fine in my experience.
Dave
From a readers' Q and A column in TV GUIDE: "If we get involved in a nuclear war, would the electromagnetic pulses from exploding bombs damage my videotapes?"