Maya's settings and rendering means very little when making models for real time. Although there are lots of polygon optimizations & texture tricks that apply across the board, how you prepare your models is very engine specific. Most game companies have their own Maya exporters that convert Maya scenes into formats compatible with their game engine. Real time renderers that let you see what your world will look like in-game are often integrated into maya. Allot of game engines also accept some of the generic files that maya can export (for instance, .obj), but to get them to look good in-game often requires some additional setting up / programming of the engine.

There are many many restrictions for what you can do. Most of Maya's features will not be supported in game engines. At a bare minimum, models, single layer diffuse textures, and basic light settings are compatible, beyond that its engine & file format specific.