It's interesting - the colours are kind of garish - which I like. It might be nice to have some broad areas of lighter colours to contrast against the night sky - maybe some Bladerunner style billboards or the like.

With the panther, it kind of reminds me of an old Roxy music cover. To be honest the panther looks very stiff. The foot and his ears just don't look very realistic to me and the expression on his face seems a bit cartoony. I might lose the panther from the image - it just seems a little bit cliched at the moment and is really detracting from the rest of your picture.