the mouse doesn't work anymore just per normal use?
i'd recommend uninstalling the game, and see if that changes anything. if it does, then the game is causing a problem...
if it doesn't, then it's the mouse. try installing a wired mouse and see if that works. also, do the keyboard and mouse both communicate with the computer using the same device? (infrared, radio, bluetooth, etc.) if so, but the keyboard still works, then your mouse may have just died. it happens. but still, try reinstalling your wireless mouse drivers and see if that does anything. working without a mouse isn't impossible, just annoying
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