I'd start with a camera, add an image plane to it and map a good starfield to it. Use that as the furthest most stars
. Now you can use the PaintEffects in the workspace to paint other stars
and galaxies and space gas. Add some bits of space debris and perhaps a moon or planet. Maybe a volumetric pointlight as a sun? Remember space is very dark so don't be afraid to use that to your advantage.
If you can't find a good image to use as an image plane, create your own with PaintEffects. Paint on a black canvas some stars
, galaxies, and space gas, then save it out, switch back to the perspective view, create a camera, create an image plane for it, and use the image you just created
Red bellows of flame have blackened my stones
Convulsing my frame and cracking my bones
Hell's dragons of steel who roar in their chains
Crawl into my caves to suck out my veins.....
-The Mountain P.F.M.