For me at least.

1) The snap function stops working properly. I'll try and snap to a vert, and it snaps to a vert somewhere else. Does so until I save and reload.

2) Unloads plugins. I frequently have to reload mental ray, although it is always checked as auto-load.

3) The Round Tool and the Circular Fillet won't work properly on anything other than very simple geometry. Maybe it's only supposed to work in those situations, but I find it quite annoying.

Just a wee rant. Anyone else came across these or have any others?

Cheers,

gubar