honestly for me it's not a backup if it's in the same physical location as you are. I use amazon s3 and amazon glacier to backup everything that's large data. All my data is saved on a linux nas then bash scripts do the uploads when i'm asleep

For day to day stuff like Maya project files and images i'm working on i use dropbox i just save everything in my dropbox folder and it's sent straight to dropboxes servers.

My linux nas also has two drives and mirrors everything in case the first drive goes down. That's about all i do. I store about a TB of data at amazon and pay around 15 bux a month.

Dave