"Hoping to lure a Predator clan to Antarctica using Alien eggs, a rogue team of scientists are caught in an intergalactic war between the two extremely violent species. " - imdb

Well, I'm not betting, but let me put a little twist on it. Weaver wants to make one last movie to give her/her character some closure, ie kill her. I think Scott was considering it. Weaver has not been named as an AvP cast member, which suggests Aliens4.