Hmmm...

By the edge of the hand, I assume you mean the 5 sided poly right by the thumb?

And if so how would a poly on the other side of the hand affect an edge loop I'm trying to insert near the pinke finger.



https://i57.tinypic.com/1r9mjd.jpg

And im sorry if I don't understand what ur saying, I'm still new so I'mt not sure how this would affect the other side of the model even though it might be obvious