This is a longshot, but try lowering the audio hardware acceleration 1 step. It's usually default set to max which can cause audio stutter and the likes in games.
If you're using windows goto:
1. Settings -> Control panel -> Sounds And Multimedia Properties
2. Click the Audio Tab
3. Under Sound Playback click the Advanced button
4. Goto Performance tab
5. Lower hardware acceleration just 1 step.
If this doesn't sort the problem then revert to original setting.