Anyone else have a problem like this?

When I start up Maya, if the only window open is the perspective window, it runs just fine. Zoom, rotate, move, etc. Just fine.

The second I change (spacebar change) to the 4-panel view, and then change back, it gets god-awful slow. I can't quite figure this one out. It's slow even if nothing is on screen. And I mean, unusably slow. I'm talking close to a second delay for each movement.