dkouts yeah you can make blend shaped, for hands if you want but it will be a lot of work. You have to make copies of the oringinal hand, then model each one of them into the shapes you want (index curl, fist etc)
I would suggest you just make a hand skeleton then bind the hand and use the set driven key to make your finger shapes. Using blend shapes on the hand will take you a very long time.
Its faster to make the skeleton for the fingers and bind, then making each hand shape.
I am enough of an artist to draw freely upon my imagination, knowledge is limited, imagination encircles the world. (Albert Einstein)