I was finishing up a rigging a model and I came across this problem. This issue is file specific, and not a default settings issue (it works on other types/versions files).
[See Attached Image]
When in the 4 pane view, I can see my rigged model and all it's parts in the perspective view.
In all other panes I do not see the Grid, the model, the skeleton at all. I only see the selection handles for the rigged model.
I cannot select the selection handles in the orthographic panes, only in the perspective view.
When selecting a piece of the mesh in the perspective view, and when I press "F" in the other views to focus on the selected object I see the object for split second as it zooms to it. Then it disappears...
Grid is on in all of the panes (per the menus), yet you can only actually see it in the perspective view.
The tool handles appear in the perspective view but not in the other views.
I don't think it's a driver issue because it works with other files. This one file must have some pane settings saved.